CircRNA Synthesis Market Size, Share and Forecast 2034
CircRNA Synthesis Market Growth, Size, Trends Analysis - By Product & Service, By Application, By End-use - Regional Outlook, Competitive Strategies and Segment Forecast to 2034
| Published: Jun-2025 | Report ID: HLCA25174 | Pages: 1 - 245 | Formats*: |
| Category : Healthcare | |||
CircRNA Synthesis Market Introduction and Overview
According to SPER Market Research, the Global CircRNA Synthesis Market is estimated to reach USD 806.01 million by 2034 with a CAGR of 16.18%.
The report includes an in-depth analysis of the Global CircRNA Synthesis Market, including market size and trends, product mix, Applications, and supplier analysis. The Global CircRNA Synthesis Market was valued at USD XX billion in 2024 and is expected to grow at a CAGR of XX% from 2025 to 2034. Due to a number of important variables, the circular RNA (circRNA) synthesis sector is expanding significantly. The intrinsic benefits of circular RNAs over conventional linear mRNAs, including improved molecular stability, extended and amplified protein expression, and decreased degradation susceptibility, are one of the main motivators. Furthermore, circRNAs can be manufactured more cheaply and efficiently, which makes them very appealing for use in advanced gene therapy, vaccines, and medicines.
By Product & Services Insights
Due to advancements in reagent formulations and kit designs, including better enzymatic reactions for RNA circularisation and buffers that are more dependable and user-friendly, reagents and kits now account for the majority of the market. A further factor driving demand for these technologies is the increasing interest in circRNA-based therapies, especially in oncology and vaccine development. To meet the growing demand, businesses such as GenScript and New England Biolabs are aggressively growing their reagent and kit offerings, which is propelling the expansion of this sector of the circRNA synthesis market.
By Application Insights
Since circRNAs have unique benefits for medical applications, such as increased stability, longer protein expression, and decreased immunogenicity when compared to linear RNA, therapeutics development is a key factor driving the circRNA synthesis sector. Because of these characteristics, circRNAs are very appealing for use in cancer treatments, uncommon genetic disease treatments, and next-generation vaccinations. With continuous attempts to address unmet clinical requirements in areas like mRNA vaccine enhancements and tailored cancer medicines, companies like Orna Therapeutics and Circio are leading the way in the development of circRNA-based therapeutics.
Regional Insights
Due to strong developments in RNA-based treatments and the rising incidence of chronic illnesses including cancer and neurological diseases, North America leads the world market for circRNA production. Innovation is being stimulated by government support for RNA research, especially in the U.S., and investments from biotech companies. The region's circRNA therapies sector is growing because to the presence of important players and comprehensive clinical trials.
Market Competitive Landscape
The Global CircRNA Synthesis Market is dominated by established players such as Amerigo Scientific, Applied Biological Materials Inc., BOC Sciences, Creative Biolabs, Creative Biogene, GeneCopoeia, Inc., GenScript, Guangzhou Geneseed Biotech. Co., Ltd., LGC Biosearch Technologies, and SBS Genetech as well as a number of small and medium-sized companies. These businesses are expanding as a result of burgeoning therapeutic uses, robust R&D, strategic alliances, and increased demand for circRNA technologies.
Recent Developments:
- Circio further solidified its focus on gene therapy in April 2024 when it revealed the successful in vivo proof-of-concept for its circVec circular RNA platform technology.
- Abogen Biosciences revealed in August 2024 that they had developed the Cis-method, a highly effective RNA circularisation cis-splicing method that makes it possible to produce circular RNA.
- Circio and Neoregen Biotech announced in October 2023 that they would begin a research partnership aimed at creating novel circular RNA (circRNA) treatments with Circio's exclusive circVec technology. By contrasting it with currently available commercial delivery methods, the partnership will assess how well Neoregen's NICT (Neoregen Intra-Cellular Delivery Technology) delivery system enhances cellular absorption and nuclear transfer of circVec vectors.
Scope of the report:
| Report Metric | Details |
| Market size available for years | 2021-2034 |
| Base year considered | 2024 |
| Forecast period | 2025-2034 |
| Segments covered | By Product & Service, By Application, By End-use |
| Regions covered | North America, Latin America, Asia-Pacific, Europe, and Middle East & Africa |
| Companies Covered | Amerigo Scientific, Applied Biological Materials Inc., BOC Sciences, Creative Biolabs, Creative Biogene, GeneCopoeia, Inc., GenScript, Guangzhou Geneseed Biotech. Co., Ltd., LGC Biosearch Technologies, and SBS Genetech |
Key Topics Covered in the Report
- Global CircRNA Synthesis Market Size (FY’2021-FY’2034)
- Overview of Global CircRNA Synthesis Market
- Segmentation of Global CircRNA Synthesis Market by Product & Service (Reagents & Kits, Instruments, Services)
- Segmentation of Global CircRNA Synthesis Market by Application (Therapeutics Development, Drug Discovery, Other Applications)
- Segmentation of Global CircRNA Synthesis Market by End Use (Pharmaceutical & Biotechnology Companies, Academic & Research Institutes, Others)
- Statistical Snap of Global CircRNA Synthesis Market
- Expansion Analysis of Global CircRNA Synthesis Market
- Problems and Obstacles in Global CircRNA Synthesis Market
- Competitive Landscape in the Global CircRNA Synthesis Market
- Details on Current Investment in Global CircRNA Synthesis Market
- Competitive Analysis of Global CircRNA Synthesis Market
- Prominent Players in the Global CircRNA Synthesis Market
- SWOT Analysis of Global CircRNA Synthesis Market
- Global CircRNA Synthesis Market Future Outlook and Projections (FY’2025-FY’2034)
- Recommendations from Analyst
1. Introduction
- 1.1. Scope of the report
- 1.2. Market segment analysis
2. Research Methodology
- 2.1. Research data source
- 2.1.1. Secondary Data
- 2.1.2. Primary Data
- 2.1.3. SPERs internal database
- 2.1.4. Premium insight from KOLs
- 2.2. Market size estimation
- 2.2.1. Top-down and Bottom-up approach
- 2.3. Data triangulation
3. Executive Summary
4. Market Dynamics
- 4.1. Driver, Restraint, Opportunity and Challenges analysis
- 4.1.1. Drivers
- 4.1.2. Restraints
- 4.1.3. Opportunities
- 4.1.4. Challenges
- 5.1. SWOT Analysis
- 5.1.1. Strengths
- 5.1.2. Weaknesses
- 5.1.3. Opportunities
- 5.1.4. Threats
- 5.2. PESTEL Analysis
- 5.2.1. Political Landscape
- 5.2.2. Economic Landscape
- 5.2.3. Social Landscape
- 5.2.4. Technological Landscape
- 5.2.5. Environmental Landscape
- 5.2.6. Legal Landscape
- 5.3. PORTERs Five Forces
- 5.3.1. Bargaining power of suppliers
- 5.3.2. Bargaining power of buyers
- 5.3.3. Threat of Substitute
- 5.3.4. Threat of new entrant
- 5.3.5. Competitive rivalry
- 5.4. Heat Map Analysis
6. Competitive Landscape
- 6.1. Global CircRNA Synthesis Market Manufacturing Base Distribution, Sales Area, Product Type
- 6.2. Mergers & Acquisitions, Partnerships, Product Launch, and Collaboration in Global CircRNA Synthesis Market
7. Global CircRNA Synthesis Market, By Product (USD Million) 2021-2034
- 7.1. Reagents
- 7.2. Kits
8. Global CircRNA Synthesis Market, By Application (USD Million) 2021-2034
- 8.1. Therapeutics Development
- 8.2. Drug Discovery
- 8.3. Other Applications
9. Global CircRNA Synthesis Market, By End Use (USD Million) 2021-2034
- 9.1. Pharmaceutical & Biotechnology Companies
- 9.2. Academic & Research Institutes
- 9.3. Others
10. Global CircRNA Synthesis Market, (USD Million) 2021-2034
- 10.1. Global CircRNA Synthesis Market Size and Market Share
11. Global CircRNA Synthesis Market, By Region, (USD Million) 2021-2034
- 11.1. Asia-Pacific
- 11.1.1. Australia
- 11.1.2. China
- 11.1.3. India
- 11.1.4. Japan
- 11.1.5. South Korea
- 11.1.6. Rest of Asia-Pacific
- 11.2. Europe
- 11.2.1. France
- 11.2.2. Germany
- 11.2.3. Italy
- 11.2.4. Spain
- 11.2.5. United Kingdom
- 11.2.6. Rest of Europe
- 11.3. Middle East and Africa
- 11.3.1. Kingdom of Saudi Arabia
- 11.3.2. United Arab Emirates
- 11.3.3. Qatar
- 11.3.4. South Africa
- 11.3.5. Egypt
- 11.3.6. Morocco
- 11.3.7. Nigeria
- 11.3.8. Rest of Middle-East and Africa
- 11.4. North America
- 11.4.1. Canada
- 11.4.2. Mexico
- 11.4.3. United States
- 11.5. Latin America
- 11.5.1. Argentina
- 11.5.2. Brazil
- 11.5.3. Rest of Latin America
12. Company Profile
- 12.1. Amerigo Scientific
- 12.1.1. Company details
- 12.1.2. Financial outlook
- 12.1.3. Product summary
- 12.1.4. Recent developments
- 12.2. Applied Biological Materials Inc
- 12.2.1. Company details
- 12.2.2. Financial outlook
- 12.2.3. Product summary
- 12.2.4. Recent developments
- 12.3. BOC Sciences
- 12.3.1. Company details
- 12.3.2. Financial outlook
- 12.3.3. Product summary
- 12.3.4. Recent developments
- 12.4. Creative Biolabs
- 12.4.1. Company details
- 12.4.2. Financial outlook
- 12.4.3. Product summary
- 12.4.4. Recent developments
- 12.5. Creative Biogene
- 12.5.1. Company details
- 12.5.2. Financial outlook
- 12.5.3. Product summary
- 12.5.4. Recent developments
- 12.6. GeneCopoeia, Inc.
- 12.6.1. Company details
- 12.6.2. Financial outlook
- 12.6.3. Product summary
- 12.6.4. Recent developments
- 12.7. GenScript
- 12.7.1. Company details
- 12.7.2. Financial outlook
- 12.7.3. Product summary
- 12.7.4. Recent developments
- 12.8. Guangzhou Geneseed Biotech. Co., Ltd.
- 12.8.1. Company details
- 12.8.2. Financial outlook
- 12.8.3. Product summary
- 12.8.4. Recent developments
- 12.9. LGC Biosearch Technologies
- 12.9.1. Company details
- 12.9.2. Financial outlook
- 12.9.3. Product summary
- 12.9.4. Recent developments
- 12.10. SBS Genetech
- 12.10.1. Company details
- 12.10.2. Financial outlook
- 12.10.3. Product summary
- 12.10.4. Recent developments
- 12.11. Others
13. Conclusion
14. List of Abbreviations
15. Reference Links
SPER Market Research’s methodology uses great emphasis on primary research to ensure that the market intelligence insights are up to date, reliable and accurate. Primary interviews are done with players involved in each phase of a supply chain to analyze the market forecasting. The secondary research method is used to help you fully understand how the future markets and the spending patterns look likes.
The report is based on in-depth qualitative and quantitative analysis of the Product Market. The quantitative analysis involves the application of various projection and sampling techniques. The qualitative analysis involves primary interviews, surveys, and vendor briefings. The data gathered as a result of these processes are validated through experts opinion. Our research methodology entails an ideal mixture of primary and secondary initiatives.
Frequently Asked Questions About This Report
CircRNA Synthesis Market is projected to reach USD 806.01 million by 2034, growing at a CAGR of 16.18% during the forecast period.
CircRNA Synthesis Market grew in Market size from 2025. The Market is expected to reach USD 806.01 million by 2034, at a CAGR of 16.18% during the forecast period.
CircRNA Synthesis Market CAGR of 16.18% during the forecast period.
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CircRNA Synthesis Market size is USD 806.01 million from 2025 to 2034.
CircRNA Synthesis Market is covered By Product & Service, By Application, By End-use
The North America is anticipated to have the highest Market share in the CircRNA Synthesis Market.
Amerigo Scientific, Applied Biological Materials Inc., BOC Sciences, Creative Biolabs, Creative Biogene, GeneCopoeia, Inc., GenScript, Guangzhou Geneseed Biotech. Co., Ltd., LGC Biosearch Technologies, and SBS Genetech
The report includes an in-depth analysis of the Global CircRNA Synthesis Market, including market size and trends, product mix, Applications, and supplier analysis
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